Summary
Chloroplasts are known to sustain life on earth by
providing food, fuel, and oxygen through the process of photosynthesis.
However, the chloroplast genome has also been smartly engineered to confer
valuable agronomic traits and/or serve as bioreactors for the production of
industrial enzymes, biopharmaceuticals, bioproducts, or vaccines. The recent
breakthrough in hyperexpression of biopharmaceuticals in edible leaves has
facilitated progression to clinical studies by major pharmaceutical companies.
This review critically evaluates progress in developing new tools to enhance or
simplify expression of targeted genes in chloroplasts. These tools hold the
promise to further the development of novel fuels and products, enhance the
photosynthetic process, and increase our understanding of retrograde signaling
and cellular processes.
http://www.cell.com/trends/plant-science/abstract/S1360-1385(15)00195-8?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1360138515001958%3Fshowall%3Dtrue&cc=y=